The fate of the cell cannot be predicted.Ĭontoh Soal Olimpiade Biologi IBO Nomor 3 : Match the following fates of the cell with the conditions (I to IV).Ĭ. A chemical which extends the half life of Bcl-2 is added to the cell. The cell overexpresses a form of Bcl-2 that is targeted to cell membrane only. The cell has expressed a mutant form of Apaf-1 that constitutively (always) bind Bcl-2. What will be the fate of a cell exposed to reactive oxygen species in the following conditions? This complex sequentially activates many proteases that digest cellular proteins. The released cytochrome c forms a complex with Apaf-1 and caspase 9. Reactive oxygen species cause Bcl-2 to release Apaf-1 and a third protein Bax to penetrate the mitochondrial membrane, releasing cytochrome c.
The outer membrane of mitochondria normally expresses a protein Bcl-2 on its surface.
One of the mechanisms is triggered by reactive oxygen species. There are various mechanisms by which a cell can commit suicide – a phenomenon known as “apoptosis”. Contoh Soal Olimpiade Biologi IBO Nomor 2 :
